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REFLECTIONS                        rtensio n
Hypertension Global Newsletter #3  Hype
                                   Hype
CARDIOVASCULAR DISEASE RISK
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7. Inverse salt sensitivity: An independent risk factor for cardiovascular damage in essential hypertension. Cuka E, et
   al. J Hypertens. 2022 Aug 1;40(8):1504-1512. https://pubmed.ncbi.nlm.nih.gov/35881450

8. Ten-second heart rate variability, its changes over time, and the development of hypertension. Kang J, et al.
   Hypertension. 2022 Jun;79(6):1308-1318. https://pubmed.ncbi.nlm.nih.gov/35317608

9.	High HDL (high-density lipoprotein) cholesterol increases cardiovascular risk in hypertensive patients. Trimarco V,
   et al. Hypertension. 2022 Oct;79(10):2355-2363. https://pubmed.ncbi.nlm.nih.gov/35968698

10. Seasonal variation in day-by-day home blood pressure variability and effect on cardiovascular disease incidence.
     Narita K, et al. Hypertension. 2022 Sep;79(9):2062-2070. https://pubmed.ncbi.nlm.nih.gov/35770661

TREATMENT

11. Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual
     antihypertensives in the UK (TIME study): A prospective, randomised, open-label, blinded-endpoint clinical trial.
     Mackenzie IS, et al. Lancet. 2022 Oct 22;400(10361):1417-1425. https://pubmed.ncbi.nlm.nih.gov/36240838/

12. Association of low-dose triple combination therapy vs usual care with time at target blood pressure: A secondary
     analysis of the TRIUMPH randomized clinical trial. Gnanenthiran SR, et al. JAMA Cardiol. 2022 Jun 1;7(6):645-650.
     https://pubmed.ncbi.nlm.nih.gov/35416909

13. Effect of different treatments for obstructive sleep apnoea on blood pressure. Kou C, et al. J Hypertens. 2022 Jun
     1;40(6):1071-1084. https://pubmed.ncbi.nlm.nih.gov/35703874

14. Digital therapeutics in hypertension: Evidence and perspectives. Kario K, et al. Hypertension. 2022 Oct;79(10):2148-
     2158. https://pubmed.ncbi.nlm.nih.gov/35726619

15. Trends in blood pressure treatment intensification in older adults with hypertension in the United States, 2008 to
     2018. Chiu N, et al. Hypertension. 2022 Sep 16:101161HYPERTENSIONAHA12219882. Online ahead of print. https://
     pubmed.ncbi.nlm.nih.gov/36111537

16. Statin use for the primary prevention of cardiovascular disease in adults: US Preventive Services Task Force
     recommendation statement. US Preventive Services Task Force, Mangione CM, et al. JAMA. 2022 Aug 23;328(8):746-
     753. https://pubmed.ncbi.nlm.nih.gov/35997723 (This article is covered in more detail in the recent Dyslipidaemia
     Newsletter available at Serviercardiomedicalhub.com)

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